10:30 PM – Arizona at Oregon
Saturday, October 4
12:00 PM – Texas A&M at Mississippi State
12:00 PM – Florida at Tennessee
3:30 PM – Alabama at Ole Miss
3:30 PM – Oklahoma at TCU
3:30 PM – Stanford at Notre Dame
3:30 PM – NC State at Clemson
7:00 PM – LSU at Auburn
7:30 PM – Arizona State at USC
8:00 PM – Nebraska at Michigan State
Week 1 Results: 7 Wins – 3 Losses
Week 2 Results: 8 Wins – 2 Losses
Week 3 Results: 8 Wins – 2 Losses
Week 4 Results: 8 Wins – 2 Losses
Week 5 Results: 7 Wins – 3 Losses
…..Just a little taste of what you’ll find at the Daley Gator Videos site:
PAT CONDELL: LAUGHING AT THE NEW INQUISITION
MONTY PYTHON’S FLYING CIRCUS: MINISTRY OF SILLY WALKS SKETCH
DR. PAUL VITZ: THE PSYCHOLOGY OF ATHEISM (PART 1)
Scientists at the Salk Institute have discovered an on-and-off “switch” in cells that may hold the key to healthy aging. This switch points to a way to encourage healthy cells to keep dividing and generating, for example, new lung or liver tissue, even in old age.
In our bodies, newly divided cells constantly replenish lungs, skin, liver and other organs. However, most human cells cannot divide indefinitely – with each division, a cellular timekeeper at the ends of chromosomes shortens. When this timekeeper, called a telomere, becomes too short, cells can no longer divide, causing organs and tissues to degenerate, as often happens in old age. But there is a way around this countdown: some cells produce an enzyme called telomerase, which rebuilds telomeres and allows cells to divide indefinitely.
In a new study published September 19th in the journal Genes and Development, scientists at the Salk Institute have discovered that telomerase, even when present, can be turned off.
……………………….Victoria Lundblad and Timothy Tucey
“Previous studies had suggested that once assembled, telomerase is available whenever it is needed,” says senior author Vicki Lundblad, professor and holder of Salk’s Ralph S. and Becky O’Connor Chair. “We were surprised to discover instead that telomerase has what is in essence an ‘off’ switch, whereby it disassembles.”
Understanding how this “off” switch can be manipulated – thereby slowing down the telomere shortening process – could lead to treatments for diseases of aging (for example, regenerating vital organs later in life).
Lundblad and first author and graduate student Timothy Tucey conducted their studies in the yeast Saccharomyces cerevisiae, the same yeast used to make wine and bread. Previously, Lundblad’s group used this simple single-celled organism to reveal numerous insights about telomerase and lay the groundwork for guiding similar findings in human cells.
“We wanted to be able to study each component of the telomerase complex but that turned out to not be a simple task,” Tucey said. Tucey developed a strategy that allowed him to observe each component during cell growth and division at very high resolution, leading to an unanticipated set of discoveries into how–and when–this telomere-dedicated machine puts itself together.
Every time a cell divides, its entire genome must be duplicated. While this duplication is going on, Tucey discovered that telomerase sits poised as a “preassembly” complex, missing a critical molecular subunit. But when the genome has been fully duplicated, the missing subunit joins its companions to form a complete, fully active telomerase complex, at which point telomerase can replenish the ends of eroding chromosomes and ensure robust cell division.
Surprisingly, however, Tucey and Lundblad showed that immediately after the full telomerase complex has been assembled, it rapidly disassembles to form an inactive “disassembly” complex – essentially flipping the switch into the “off” position. They speculate that this disassembly pathway may provide a means of keeping telomerase at exceptionally low levels inside the cell. Although eroding telomeres in normal cells can contribute to the aging process, cancer cells, in contrast, rely on elevated telomerase levels to ensure unregulated cell growth. The “off” switch discovered by Tucey and Lundblad may help keep telomerase activity below this threshold.
The sympathetic news media is avoiding mentioning his name, instead they are blaming the lack of a football intro for the massive collapse in ratings Sunday night for President Barack Obama’s appearance on CBS’ 60 Minutes. Americans turned away from watching Obama even though he was being interviewed about the nation’s new war on ISIS.
For example, Deadline Hollywood didn’t even mention Obama’s 60 Minutes interview when reporting on the drop in viewers.
“With no football lead-in, CBS’ Sunday lineup fell from last week. As expected, the drop was steepest at 7 PM, with 60 Minutes (1.1) off by 69% from last Sunday, when it directly followed the game.”
Also, Variety avoided mentioning Obama on 60 Minutes.
“At CBS, “60 Minutes” (1.1/4 in 18-49, 9.2 million viewers overall) dropped off sharply from last week when it had the end of the Denver-Seattle football game as a lead-in, and was also down about 20% from last year.”
The Los Angeles Times likewise did not name Obama.
“”60 Minutes” didn’t fare as well. With a rating of 1.1 in the key demo, the show was down 69% from last week’s season premiere. About 9.1 million people tuned in.”
Neither did Broadcasting and Cable:
“Newsmagazine 60 Minutes drew a 1.1, down sharply from last week, when it received a big lead-in from football overruns”
“On CBS, 60 Minutes scored a 1.1, down 69 percent from last week’ s NFL boosted 3.5 adults 18-49 rating.”
“CBS took fourth place in ratings with a 1.3/4 and third in total viewers with 10.7 million. “60 Minutes” at 7 posted a 1.1/4 with 9.2 million total viewers, while the freshman drama “Madam Secretary” the following hour dropped off 30 percent from last week’s series premiere, posting a 1.4/4 with 12.7 million total viewers.”
Last week CBS sent out a press release bragging on 60 Minutes’ ratings, as reported by the Futon Critic.
There appears to be no reports of 60 Minutes bragging about the ratings for Obama’s 60 Minutes show.
A gold star goes to Hal Boedeker at the Orlando Sentinel for apparently being the only reporter to mentioned Obama in reporting on 60 Minutes’ ratings however he did not mention the huge ratings drop.
“And “60 Minutes” had 9.2 million for an interview with President Barack Obama.”
Change Obama to Bush and one can imagine how the media would have been reporting the 60 Minutes ratings collapse: Americans Tune out Bush as He Drags U.S. in Another War.
A new Government Accountability Institute (GAI) report reveals that President Barack Obama has attended only 42.1% of his daily intelligence briefings (known officially as the Presidential Daily Brief, or PDB) in the 2,079 days of his presidency through September 29, 2014.
The GAI report also included a breakdown of Obama’s PDB attendance record between terms; he attended 42.4% of his PDBs in his first term and 41.3% in his second.
The GAI’s alarming findings come on the heels of Obama’s 60 Minutes comments on Sunday, wherein the president laid the blame for the Islamic State’s (ISIS) rapid rise squarely at the feet of his Director of National Intelligence James Clapper.
“I think our head of the intelligence community, Jim Clapper, has acknowledged that I think they underestimated what had been taking place in Syria,” said Obama.
According to Daily Beast reporter Eli Lake, members of the Defense establishment were “flabbergasted” by Obama’s attempt to shift blame.
“Either the president doesn’t read the intelligence he’s getting or he’s bullshitting,” a former senior Pentagon official “who worked closely on the threat posed by Sunni jihadists in Syria and Iraq” told the Daily Beast.
On Monday, others in the intelligence community similarly blasted Obama and said he’s shown longstanding disinterest in receiving live, in-person PDBs that allow the Commander-in-Chief the chance for critical followup, feedback, questions, and the challenging of flawed intelligence assumptions.
“It’s pretty well-known that the president hasn’t taken in-person intelligence briefings with any regularity since the early days of 2009,” an Obama national security staffer told the Daily Mail on Monday. “He gets them in writing.”
The Obama security staffer said the president’s PDBs have contained detailed threat warnings about the Islamic State dating back to before the 2012 presidential election.
“Unless someone very senior has been shredding the president’s daily briefings and telling him that the dog ate them, highly accurate predictions about ISIL have been showing up in the Oval Office since before the 2012 election,” the Obama security staffer told the Daily Mail.
This is not the first time questions have been raised about Obama’s lack of engagement and interest in receiving in-person daily intelligence briefings. On September 10, 2012, the GAI released a similar report showing that Obama had attended less than half (43.8%) of his daily intelligence briefings up to that point. When Washington Post columnist Marc Thiessen mentioned the GAI’s findings in his column, then-White House Press Secretary Jay Carney dubbed the findings “hilarious.” The very next day, U.S. Libyan Ambassador Chris Stevens and three American staff members were murdered in Benghazi. As Breitbart News reported at the time, the White House’s very own presidential calendar revealed Obama had not received his daily intel briefing in the five consecutive days leading up to the Benghazi attacks.
Ultimately, as ABC News reported, the White House did not directly dispute the GAI’s numbers but instead said Obama prefers to read his PDB on his iPad instead of receiving the all-important live, in-person briefings.
Now, with ISIS controlling over 35,000 square miles of territory in its widening caliphate in Iraq and Syria, and with Obama pointing fingers at his own Director of National Intelligence James Clapper for the rise of ISIS, the question remains whether a 42% attendance record on daily intelligence briefings is good enough for most Americans.